Cocaine Changes in Brain Reversed by Amino Acid, Animal Study Suggests

Researchers from the Medical University of South Carolina say that a common amino acid could be used to undo the brain-circuitry changes wrought by cocaine use and reduce craving for the drug, Science Daily reported Oct. 23.

“Our finding suggests a promising therapeutic strategy for cocaine addiction, for which there is no approved treatment,” said lead researcher Khaled Moussawi.

Moussawi and colleagues administered the amino acid N-acetlycysteine (NAC) to lab rats addicted to cocaine and found that the rats stopped seeking drugs, even when given drug-associated cues. NAC is involved in the pathway for the neurotransmitter glutamate.

The study findings were unveiled at the recent annual meeting of the Society of Neuroscience.

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Cocaine Changes in Brain Reversed by Amino Acid, Animal Study Suggests

Researchers from the Medical University of South Carolina say that a common amino acid could be used to undo the brain-circuitry changes wrought by cocaine use and reduce craving for the drug, Science Daily reported Oct. 23.


“Our finding suggests a promising therapeutic strategy for cocaine addiction, for which there is no approved treatment,” said lead researcher Khaled Moussawi.


Moussawi and colleagues administered the amino acid N-acetlycysteine (NAC) to lab rats addicted to cocaine and found that the rats stopped seeking drugs, even when given drug-associated cues. NAC is involved in the pathway for the neurotransmitter glutamate.


The study findings were unveiled at the recent annual meeting of the Society of Neuroscience.

Leave a Reply

Please read our comment policy and guidelines before you submit a comment. Your email address will not be published. Thank you for visiting Join Together.

Required fields are marked *


*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>