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Random drug testing of middle-school students may help prevent substance abuse, a six-year study of New Jersey students suggests.

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A California state senator has proposed legislation that would allow misdemeanor charges to be filed in cases of simple possession of heroin and cocaine, instead of felony charges.

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Youth who become active in Alcoholics Anonymous-related helping while they are in treatment are less likely to test positive for alcohol and drugs during treatment, a new study finds.

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Mapping the location of alcohol outlets, drug activity and violent crimes could help police prevent violence, a new study suggests.

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Having a parent or sibling who has been deployed in the military increases the risk of drug and alcohol use among middle and high school students, a new study finds.

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Drug use among Ohio inmates is the highest it has been in more than a decade, according to The Columbus Dispatch. Most of the inmates who tested positive for drugs in 2012 used marijuana.

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A new study finds children and teens who overeat are more likely to start using marijuana and other drugs, compared with their peers who don’t eat too much.

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Drug abuse or heavy drinking can cause long-term changes in the heart, arteries or blood that increase the risk of stroke in young adults, a new study finds.

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The Food and Drug Administration is launching a new campaign to warn consumers to avoid buying medicine from fraudulent online pharmacies. The National Association of Boards of Pharmacy estimates that less than 3 percent of online pharmacies meet state and federal laws.

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Substance abuse among members of the U.S. military and their families has become a public health crisis, according to a new report. The Defense Department’s approaches to preventing and treating substance abuse are outdated, the report states.

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