Antidepressants Don't Prevent Smoking Among ADHD Patients, Study Says

The antidepressant bupropion is ineffective in preventing smoking among youths with attention-deficit/hyperactivity disorder (ADHD), Reuters reported Aug. 29.


Bupropion is sold as Zyban as a stop-smoking aid and as Wellbutrin for treating depression or seasonal-affective disorder. Since youth with ADHD are at high risk for smoking, it was hoped that the drug would have a preventive effect in this population.


But researchers found that a placebo group had a far lower rate of nicotine exposure than a group receiving bupropion. On the other hand, stimulants did appear to cut smoking risk.


The study was published in the July 2007 issue of the Journal of Clinical Psychiatry.

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